Key Benefits
THE FIRST AND ONLY PROVEN ALTERNATIVE TO AUTOGRAFT IN ANKLE AND HINDFOOT ARTHRODESIS
Proven
- Level 1 evidence from largest F&A clinical trial ever conducted
- Equivalent improvements in clinical outcomes, compared to the gold standard autograft1
Labeled
- Class III combination product labeled for ankle and hindfoot arthrodesis
Unique
- Bioengineered human PDGF-BB stimulates multiple aspects of healing in response to injury
- rhPDGF-BB is highly purified with consistent biological potency; allograft and autograft are highly variable in quality and potency2,3,4,5
Safe
- In commercial use since 2009 (Canada)
- Eliminates risks, morbidities, costs associated with autograft harvest
1. DiGiovanni, et al. JBJS (2013).
2. Fiedler, et al. J Cell Biochem (2002).
3. Ozaki, et al. J Stem Cells & Dev (2007).
4. Bouletreau, et al. Plast Reconstr Surg (2002).
5. Hollinger, et al. JBJS (2008).
2. Fiedler, et al. J Cell Biochem (2002).
3. Ozaki, et al. J Stem Cells & Dev (2007).
4. Bouletreau, et al. Plast Reconstr Surg (2002).
5. Hollinger, et al. JBJS (2008).
For reimbursement information, visit www.wright.com/reimbursement.
AUGMENT® Bone Graft
AUGMENT® Injectable
SUPPORTING CLINICAL EVIDENCE
- DiGiovanni, CW et al. | J Bone Joint Surg Am. 2013
- Friedlaender, GE et al. | Curr Pharm Des. 2013
- Solchaga, LA et al. | Clin Drug Investig. 2013
- Glazebrook, M et al. | Techniques in Foot & Ankle Surgery 2012
- DiGiovanni, CW et al. | Expert Rev Med Devices 2012
- DiGiovanni, CW et al. | Foot Ankle Int. 2011
- DiGiovanni, CW et al. | Foot Ankle Clin. 2010
- Daniels, T et al. | Foot Ankle Int. 2010
- Hollinger, JO et al. | J Bone Joint Surg Am. 2008
- Nevins, M et al. | J Periodontol 2005
- Solchaga, LA et al. | J Tissue Eng. 2012
- Caplan, AI et al. | J Orthop Res. 2011
- Verma, R et al. | Current Ortho Practice 2011
- Pountos, I et al. | J Orthop Trauma 2010
- Moore, DC et al. | J Bone Joint Surg Am. 2009
- Al-Zube, L et al. | J Orthop Res. 2009
- McCarthy, HS et al. | J Cell Physiol. 2009
- Tokunaga, A et al. | J Bone Miner Res. 2008
- Sanchez-Fernandez, MA et al. | PLoS One. 2008
- Hollinger, JO et al. | J Orthop Res. 2008
- Ozaki, Y et al. | Stem Cells Dev. 2007
- Kilian, O et al. | Growth Factors 2005
- Fiedler, J et al. | J Cell Biochem. 2004
- Mehrotra, M et al. | J Cell Biochem. 2004
- Kilian, O et al. | Eur J Med Res. 2004
- Bouletreau, PJ et al. | Plast Reconstr Surg. 2002
- Fiedler, J PJ et al. | J Cell Biochem. 2002
- Zhang, Z PJ et al. | Biochem Biophys Res Commun. 1998
- Glazebrook, M PJ et al. | Foot Ankle Int. 2013
- Baumhauer, JF PJ et al. | Foot Ankle Int. 2013
- Baumhauer, J PJ et al. | Foot Ankle Int. 2013
- DiGiovanni, CW et al. | J Bone Joint Surg Am. 2016
- LIN, SS ET AL. | J
AM ACAD ORTHOP SURG. 2016
- KRAUSE, F ET AL. |
JBJS 2016
- DiGiovanni, CW et al. | J Bone Joint Surg Am. 2013